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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8875d21224c14fbcc077cf603571504bb21d9ec978e2ef98497c98591e4e7a3d' 
  AND token = '7Mdqp7A2DQgsBTc7dkxNtugLoAUqNFi69IGjW1b08Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}