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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b0e3e1b09f567f45aef24009e0ed447d2bcc634d23dcb4ce538f24e2c8491d8' 
  AND token = '1YMDEsJ5Rpwasdq43vmlx5ZBmEH6FmXjYXJj0nwwKf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}