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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290af59e6fcce16fdd0c85a021a831b51fa3161be35131cdf0ad0855b77e39c0' 
  AND token = 'Sjxla1K22OhX4Hs+q8mgoy8dlGpWk5az1btXbPEv92U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}