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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27d93f26f6fb015c6a45e566fc74a81bbf6ff7cf4dab72997a63ef8d951f5364' 
  AND token = 'Rm1eYof9GNEUt1J6fNI9ZWMsiSN7tGvYMKtwW+7HnM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}