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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4442e95e98b4fa8ddc0a9f35598bef2602b0b86458087dd8ddc0a36e1a093055' 
  AND token = 'YV2eiQcnwh3jv/w6ge/VqT4t08whlmS2kqxhYg1Xihk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}