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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eaed745ee454ed0b72cb14c08c6691931e110e17969482628ddec64d1bb32a2' 
  AND token = 'sc33ND2ZYo3FwopVWerxqjmBjsEnZZfDS5ZnKNwkDso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}