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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c9cafaefd299496074f170273af8260051fda9ea79a9dcfcadc0e8aa6b4a50' 
  AND token = 'l1LnFogKGPywOzFUzWWXGukM8AzcEnCmk62VSGno9cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}