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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6604e7dd6c7f0e0fb81d22b05d92fdd35a28b47c611eafe0e042908cf6070ed' 
  AND token = '1Yu8OQz+aOk3Og+k+gSlLAh8MoMA+L9BS0oLblW2RMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}