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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e01e38cc51a78914d44c31d1f2b8229ae6f5308eea2c29770f4fe560c391899' 
  AND token = 'Rodx8ShvAgC6uRrVkySOZUZ1q8Slu9r0ICxF8bOklq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}