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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaf4802c1c02538859fcf4914ff2483adc4b54b5a14c6c13860379b4dd48fd0c' 
  AND token = 'OJsGmBTD9/etqag99I+ebq8Hpq4w3fNANKs5SOkf3GM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}