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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7744b72c1bd0ea8544ce64c832740a4dee2066804760e8b6d5c394fbde363751' 
  AND token = 'NHAZJxmuI+wt0Pd1j1mFpFgIjmPBI86lJfG2ItPLAQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}