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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ced7c59582ad9d4a50791f1e61f4ac084f92307f2920274c730dde216f9c5b4' 
  AND token = 'ptzY2+I2hf3D4DV4aOcHW/3gUAjOyRLEwKPeRc4FYsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}