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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ae09b9f74d0c75f88a3673235d51a98a97dd659878299550c64593635ed335d' 
  AND token = 'HNx0E8SnQOfQuEVKrNrQ/2GV9gUeWuL4tREkOGZWCiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}