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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08ad45c6bc39cd1de44412887da7331dcf21287c89be300657b365a3d5e3e5cf' 
  AND token = 'vkBx0fBgoCSAsNjDswGk11BnVh1aYHkgoNQM0mkgii0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}