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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6667875661dc6ba9a2329b9b9688dd6081f683f7ddbc94562d965dbd75b7be10' 
  AND token = 'ulm5WqIs0yDIjfFmSmcQ8E+8XSmQOAa5bopMCmjl280=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}