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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f20250d685e67d7d4631219033ccba86546efde1c1c4e6167dfd7650ec27a43' 
  AND token = '5muU1fIIMf+Cm6AmcRhhG3615pAVZPpj+bKoAYIPv1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}