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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23f661a38525678854ac060e87edcf736d4d013337cd9e13b7e4bed1299f1926' 
  AND token = '7QT0OTrbG9gsaBmPdWcKrUmlL257lbwGn42D+nZ6w3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}