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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eb9141cddf57b12b7ecdd05ab72163f8f2db228595eaf994105fbcf415182d7' 
  AND token = 'qXfiwHaI/OQ2LDbbRT7t1VnnDqAcS+4ByJFFLarGIag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}