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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '469aa68814935e5c42f3b0a863e8ad5081267eb6b1188dfe9021e7df73feb910' 
  AND token = 'R7HoPuqBKxU6TOJjzxAht0HEJGOox43Uyv85/c98euA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}