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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b29afd59b3a27ce200e529886fd2b4d390afb74b750a44a9f3d519739d8ca870' 
  AND token = 'XO5VxdNQA7Fbr+RGR+dxxCowfr+Z9lZSMm/8K50FpsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}