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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6255a440de8e7b74f2f80499c66f58c2ec4d2614a7d1d9206cc186b6061bdcc1' 
  AND token = '3XOeM03DExq3PeOjGwtkdxGlNZ/JQKrVxztz4kV1yDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}