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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1ceeefd38571950a8b9b438080ab8a078d78403bc7a283d87f51b9508f4aeb4' 
  AND token = 'khTvrhnvaVv7ipAZe5HNTQ8psjb9N6NbYVr/67KCZ0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}