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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6b5e84b849075a28f5e8ff2aed4c04f05453cdd15741805c1da6b844cc9c6d' 
  AND token = '+ZGIJovhJkun8VKmT5l9NyBxWwAn5l/5en6Edj1MOyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}