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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ced73b8b9f899e75b17f198fe4248bcf783d688f08dc5c5e5815de8382434017' 
  AND token = 'hIumo7Y0c7tNZ5QyTl5LrYTP70I/mpg/tffFSsOrPoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}