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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8996e8d881ef48bc1626c6880916bebef966df4e76cda45cc2df993e58ff4d1e' 
  AND token = 'yxz27XYGGFOw59MKrWeq4N1lZHcpMr2gKtncrDKnfs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}