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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa8559b4bc8c66a5e39e812ff3bb0b4f9212442cf46ebe7035b6483cde499866' 
  AND token = 'ucoo2y29KFdZ/jjLl2wrnIOOhn1jfqDKEUsrwLOpI5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}