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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09515ccc4a84e2f9d1c6c35a0abf80135c8b90cc1c3f08b3acee628a0a7208e2' 
  AND token = 'EMTPSx2QFgO4G1o6hzo/gkMywKLbV3cjMMJEx5mJDqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}