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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f073c7b242da567d998af3e7da5b70db44a468ac2a35034e8069d04cc1afa395' 
  AND token = '/SIEGBHN2027OOGu3CjW9/xh3G9xJNMoq1AL0KemowU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}