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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '113b9a7c25e86e178b08be94b752aa4b10bf28d9fcf9d762987ce3c9afb648ec' 
  AND token = 'QmG9xVOlsdiQNTuXRY7HTDf6b1nir7YNgvk9QLIw01k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}