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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2386ace41a5f5783ce495fe876b5f506d126baa2c54e694662080a39b1449b2c' 
  AND token = 'VpxIE9nE7qPxW0hvyXqAYsh0C0feZ3NNUiedw4icqPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}