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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4d3ffc9fdb959b6650290f1ab6e2b24c5825b6048515864095f37bf62bca831' 
  AND token = 'f709p0hlKzTFMTGVUcFGHh+IN0b+XqA84ZOK3fl4VdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}