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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288623a3c443f5348cf2d1f084dcb8c6c6752b344805b0b58f29a1fae0c1cc86' 
  AND token = 'hpIUdCGvxjHhFv6cwhGlw0/AqrBjzCt55ALs2fvlCrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}