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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8c321f926821c877aa8778f3a54ad14d82a0ba3a97a3897f386158a58bcda4' 
  AND token = 'zA4lATu6WXTCaSz0+bW5Xxl9q0Tmk5RCExnFBgDXBA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}