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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '277c09981d52c8e934711be3cf855bb4dfdb943270908cd1a0ba92fc4ab8b658' 
  AND token = 'enDAH4NxzhJPv/8U6FunGcXMhOpq18dnvNlE0FhF7ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}