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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e78dfdacd1141a95bdc434821cb749e97edf06294c2f96f66fec8ed4cdbcff1' 
  AND token = '4xFB4MzdGfQu/6WksLPetW3oGQuMexcl3xwKi7vwl5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}