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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd445894d2e625708566b950c3539b549e3038c0aac80dc8a91eeeff3f3be18e6' 
  AND token = 'adz/PxW0DI9I1qmuP0UDiGd9OpILt3S4Pc3yYP5wQV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}