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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8722ad25d566c3f7af1c57904979d9dc6d2663520f74cbf681c93ccf97de2a5e' 
  AND token = 'rc3Nu36cvg01j21aks4zow23mkBzptlhWoSc0cM4aO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}