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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54dda2cc9d7d038433a3cdb156c0c1243cd51a059faf7d84a7c860699edd3178' 
  AND token = 'tIu4cI+VMjOVUuqbuy6sfkBfEcWYXRjq7OWt7ZplSBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}