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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3f405007445df6e49b4294f9f955e998af064796b7e23437bf298dbed226b64' 
  AND token = 'jOT7MgptLVaiMY7oaD61Xd9DXl8Vhcy/fBDsyxYkp/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}