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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8293d2533eee43e8fdbffe62527bf4592b7168d568e3c11c73d55dcfa1fee215' 
  AND token = 'nNwP2wXCqKngH6zToD5erscfB/6zVSEWB54e/XZxL1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}