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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6135fdb62f6d39c515fd795ed326a5be4c54d300a74feb778f713ebfb2c9c6f2' 
  AND token = 't1SE2EyismaVxwrctWPunvK5jTwCCHFDOgNfxnkhQAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}