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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8290801f1553cd9572c36754f49cbf505e2f8a719b7e5a40f2bee3ed162e1939' 
  AND token = 'PQSpMZj7XLSEsoB6Z+Ot6mcT775P/cTfsMfkJ570r+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}