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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1ae47eadba6b490b6eacf95bf824cba02e29ed4bdcce433a939e804bc387970' 
  AND token = 'DYzm2Wr08243PcOQUONH2Y1lccu+ht1Zf6s2jxWLRZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}