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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8916b7a38c5e7bcb39c8ceb9da411afc602d340ce90a3d110f40b9e283f3225a' 
  AND token = 'ckGoigUNOR6lEvxlAH/PixGtV5oH0Otk+uS+cMLnwmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}