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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6e40c51b2c327b98a712640dcb3e60f059e8f225b6e34a61286e6c43f7ed391' 
  AND token = 'PtlbcSOQEi0A6OEVOh5oIbLSMHTZDIfn0/LmECB0MGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}