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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '806e0722a7307adcecb2a5c2fa61e7f28c7ce6b9b10ec2437d2d650ffd737d78' 
  AND token = '2o7qo/uIdwpzM/rxHRVDFGAO2hfjG2QDM+RppOATlDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}