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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '768d3767b297c5d50b6ec13905db5fe45c2a80483021e04ffdf4b887152ce03f' 
  AND token = 'uDwnr2mBeA5O4QqvSzrCxYS2nyHTSAqwptqOmFofzxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}