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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2621f23678f0206a080e8087c7b96c622a3f3e77ae77a4d001837e52e353bac9' 
  AND token = 'qzVvP8XIJxOKg262LrQr+ISeLXeyqMj2i84lsjlF1vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}