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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed2eb48e42231ee50eccba1bf35df909cdcf14cff28c4a099bed9227a26f14f' 
  AND token = 'ypY8DbjsVh8xoTfoKa4uBu/uBmoGooKp2D8lSKb8DEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}