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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e3fa328c6d9d3e086ab2bf3aaf4430b32328f36f21457d0a7ea656308001b5a' 
  AND token = 'Ehl25T1GBqXncD/7X9NPqPpNF4iqkQIbuojVEsr3UW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}